Yes, they are different. I booked my 3 house yesterday after already having a 6 house tour. At first, I was told "You might get repeats," but when I said that the official Universal Twitter said they would be different, the girl went to a manager and confirmed they would all be different.
When I asked if I could also book multi night tickets while booking my tour, I was told they were not on sale yet, but to keep an eye out.
My guess is, Hollywood still has no idea what it is doing as far as multi night tickets go, and since we are currently sharing our announcements with Hollywood, having us announce them and Hollywood not would look bad or confuse the GP
Also, I come from out of town so I want to know too, but it is a patience game at this point.