This theme question is a catch-22.
On one hand, F&F lends itself much better to a minimally-themed, high-thrill coaster (because nondescript, vaguely industrial, back-of-house areas are a fine proxy for any number of urban environments seen in those movies). And it would pave the way for getting Supercharged out of the park and opening up that plot for something deserving of the space.
On the other hand, Ghostbusters is the much more exciting, beloved, long-lasting brand that should have significant theme park representation. But I'd argue that a minimally-themed, high-thrill coaster is not really the ideal attraction type for it.