Yikes.
That $295M budget is going to make it impossible for this movie to be profitable. There's so many films with huge budgets out here flopping left and right this month alone with Elemental and The Flash both at around $200M, Indy at $295M, and Rise of the Beasts at $200M is pretty much definitely going to lose money and it's almost like no one cares because it's just becoming so regular.
Indy would have to make probably at least $700-$800M Worldwide (which isn't going to happen if it opens that low domestically) or so just to break even. Absolutely loony spending, but the budget did get run up far higher than Disney wanted due to COVID restrictions during filming so i'll give them that at least.
'Indiana Jones 5' is targeting at least $65 million from 4,500 North American theaters in its opening weekend.
variety.com