My guesses:
1: Begins with Gameplay trailer for Challenger Pack Joker, revealed that all Challenger packs will have an Echo (with Joker's being Akechi). The Stage is Shibuya, transforming into Memento's Shibuya. Release window is Early April.
2: Pikmin 3 is revealed, and given a May release
3: Daemon X Machina is given a new trailer & release, for June
4: Assassins Creed III Remastered is revealed to be coming to Nintendo Switch for a Spring release
5: Final Fantasy VII is Shadowdropped
6: Boxboy! is Shadowdropped
7: Metroid Prime Trilogy HD is revealed for April
8: Multiple Western & Japanese Third Party titles to be revealed during direct
8: Direct concludes with 2D Zelda
9: No Fire Emblem, Luigi's Mansion 3, Super Mario Maker, Pokemon, SNES
My more guessing, on this front.
I suspect they'll want Fire Emblem to have it's own direct, to give large updates for Fire Emblem Expo, Three Houses, and Heroes. More in the sense, that they may want to give it it's own space.
SNES goes on a similar vein, especially if Nintendo is preparing a massive change for the NSM. And knowing the odds, Pokemon & SMM are both E3 based at the pure level.