My hope would be something Animal Kingdom esque. A larger river with a large lake area attached that can be used for a show.
Just looked at an overhead view of the main area of Animal Kingdom, and it’s a perfect layout style!
Going off of AK’s map for reference, you can put the hub on the main island (with a view tower to look at all of the lands), Jurassic World where Everest is (and it retains that fantastic lake seen in the Beijing concept art), WaterWorld/Fantastic Beasts where Dino-Rama/Dinosaur is, Classic Monsters where Pandora is, Nintendo in the Africa/Safari section, and DreamWorks where Kali Rapids is. Have a transit system in the rivers, a live night show on the lake, and small, border-like mini-sections between the lands, and you got yourself a good, balanced layout. Obviously, the lands aren’t to scale, but you get the point.