And the film did undergo a few changes in both director(s) and casting. Zoe Saldana is replacing America Ferrera who stepped down due to scheduling conflicts, and the character of Olga is being rewritten to be Elio's Aunt instead of his Mother.
As for the director changes, Adrian Molina was taken on to a currently undisclosed priority project, and he worked with Pete Doctor to find a suitable replacement to take the reigns, and they landed on both "Turning Red"s Domee Shi and Madeline Sharafian who directed the "Burrows" short, making this her first theatrical length directorial debut.
Pixar's chief creative officer Pete Docter explains why new sci-fi film "Elio" has new directors, what changed in the story and how Zoe Saldaña got added to the cast.
www.thewrap.com
From the sounds of things, the changes have been going pretty smoothly due to the circumstances which are pretty natural in the industry. (And not due to sheer drama/chaos.)