Theory on the very end of the episode:
So when Loki ends up back at the TVA and they have no idea who he is and he looks and the statues are already changed, my take on that is that there's already a new Kang in charge, but it's one of his more boastful and more dictator-like versions of him.
Many have theorized that Loki was simply sent to a TVA in a different timeline, because she kicked him out of the Castle *before* she killed that version of Kang, so Loki would have gone back to the regular TVA that we all had known from this season. What I think is wrong is that there's a Conquerer Kang now in charge, he wants people to know it (thus why he's using a statue of himself rather than man behind the curtain approach), and he probably wiped everyone's memories, just like the TVA did originally to keep the ruse going.
I wonder how long after this season that S2 is going to take place. You would think they would want it to be immediate given where we ended, but I don't think a S2 can come out until late 2022 at the earliest just due to how long production/post-production will take (given that production isn't slated to start until January) along with working around other shows. At that point, I have to imagine Dr. Strange 2 is going to have fixed a lot, so Season 2 may pick up at a completely different point.
Also, thinking about the future of the MCU quickly:
I think it's plausible to argue that any Marvel character in any Marvel movie ever is going to be canon during this multiversal time period. For example, it's rumored that Charlie Cox's Matt Murdock when he supposedly appears in Spidey and a few other projects will be him as a variant meaning it is the EXACT Netflix version of him. Also, as another example, remember that it was rumored that Chris Evans signed on to come back to the MCU? What if he's playing Human Torch and not Cap? Or what if he plays versions of both? With the multiverse, literally anything becomes possible. This could be how they explain why Deadpool is in the MCU now that I think about it.